Location: Main St and Civic Center Blvd, Anderson A block after the 178 split, turn right to access 178 if you missed it before. Stay straight for 76/28 Business to I-85. Location: Main St and SC 28, Anderson A few blocks later, we’ll approach Highway 28. Location: Main St and SC 28, Anderson Turn left … Continue reading U.S. Route 76, US-178 to SC-28/SC-28 Bus